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Sabtu, 28 Mei 2011

Roots Tread Dara



Systematics

Other Names: Roots Tread Dara
Plant Name Origin: Catharanthus roseus (L), Vinca rosea (L), Lochnera rosea
Family: Apocynaceae
Substance Efficacious: alkaloids: ajmalicine, serpentina, tetrahidroalstonin, vindesin, vincristine, vinblastine
Usage: Emenagoga, diabetes drugs, cancer drugs
Pemerian: No smell, taste bitter
Storage: In a well sealed containerThis plant originated from Central America, commonly planted as an ornamental plant. Vinca can grow in the open or protected in a variety of climates, are found from lowland until height of 800 m above sea level.
Herb or shrub, chronic, grow upright, reaches 120 cm tall, much branched. Stem round, the base of woody, smooth-haired, red color tengguli. Leaves single, rather thick, short-stemmed, dealing crossed. Leaf blade elliptic, tip runcng, base tapered, flat edge, pertulangan pinnate, both leaf surfaces shiny and smooth hair. Inflorescence compound, out of the end of the shaft and axillary panicles with 5 pieces of crown trumpet-shaped flowers, the color is white, pink or white with red spots in the middle. Tube fruit fruit hairy, hanging, contains many black seeds. Propagation by seed, stem or root cuttings.
Nature and BenefitsHerba slightly bitter taste, cool, somewhat poisonous (toxic), enter the liver meridian, peluruh urine (diuretic), lowers blood pressure (hypotensive), tranquilizers (sedatives), cool blood, stop bleeding (hemostatis), as well as eliminating heat and toxins. While the roots of vinca peluruh efficacious as menstruation.
Chemical IngredientsHerbs contain more than 70 kinds of alkaloids, including 28 biindole alkaloids. Anticancer components, namely as vincaleukoblastine alkaloids (vinblastine = VLB), leurosidin and catharanthine, Alkalod an efficacious hypoglycemic (lowering blood sugar levels), among others leurosin, catharanthine, lochneri, tetrahidroalstonin, vindolin and vindolinin. While the roots containing vinca alkaloids, saponins, and tannins flafonoid.
Used PartsHerbs and roots. Use fresh or dried
IndicationHerba efficacious address:

    
* High blood pressure (hypertension)
    
* Diabetes (diabetes mellitus)
    
* Diabetes bit (oliguria)
    
* Hepatitis
    
* Bleeding due to decrease in the number of platelets (primary thrombocytopenic purpua)
    
* Malaria
    
* It is hard bowel movement (constipation)
    
* Cancer: Hodgkin's disease, "s, chorionic epithelioma, acute lymphocytic leukemia, acute leukemia monostik, limfosarkoma an retikum cell sarcomas.
Roots efficacious address:

    
* Menstrual irregularities
How to UseHerba 6 - 15g boiled in 5 cups of water until the remaining 2 cups low heat. Once cool, filtered and drunk several times to run out within a day. For external use, fresh leaves added to taste and finely ground rice till mushy. Smeared on a scalded wound.
Stock FarmakologisActive compounds vinblastine and vincristine potent anticancer in leukemia, Ehrlich ascitic carsinoma liver and Walker carcinoma. Also to stop cell division (myth) of cancer at the metaphase and inhibits purine synthesis, DNA and RNA. Vimblastin especially for diseases hodgki "s and chorioepithelioma, is also effective in breast cancer, ovary (ovarian), testes and nephroblastoma. Vincristine is more effective in acute lymphocytic leukemia granulostik and, especially in acute lymphocytic leukemia and mielositik in children. Both cause mild suppression of bone marrow (the cause of decline in the number of white blood cells and platelets).
Giving stew vinca leaves (white flower) 10%, 20%, 30% and 40% with a dose of 5 ml / kg bw in rabbits can reduce their blood sugar levels nasing of 46.61%, 49.25%, 51, 62% and 58.66% compared with tolbutamide (Norma, Department of Pharmaceutical Science Faculty of Hasanuddin University, 1985)
Giving stew vinca leaves (red flowers) per oral on male white mice, hypoglycemic effect of decoction obtained yield of 15% at minute 210, 240 and 270. Stew yield 30%, hypoglycemic effects at minute 240 and 270. Relative potency leaf stew red flowering vinca that approximately half of the potential of tolbutamide relative to water. The effect is very weak when compared with tolbutamide (Suyanto, FK UGM 1992)
Example UsageHigh blood pressure, diabetes, acute lymphocytic leukemia. (Br) of fresh leaves of vinca 15g boiled in 5 cups of water until the remaining 2 cups. After chilling filtered, the result is taken twice as much in the morning and afternoon.
Side EffectsVinblastine effect of the decrease of white blood cell count (leukopenia), which returned to normal after 1-2 weeks of the drug is stopped, no appetite, nausea, vomiting, difficult bowel movements and neurokogis disorders such as insomnia, headaches, mental depression, abnormal and Sensai loss of reflexes in
Side effects of vincristine appears on the nervous system with symptoms of abnormal sensation, numbness in the limbs, pain, weakness, loss of reflexes in, impaired movement, paralysis of the eyelids (ptosis), vision (diplopia), husky and balding (alopecia). Constraints on the system also occur making blood cells, hemoglobin and platelets (platelet). decreased white blood cells 1-2 weeks after taking the drug.
Notes

    
* Outside the country has made herb vinca namely injecting drug vincristine and vinblastine ijeksi
    
* Pregnant women are prohibited from using these herbs

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